5-(2-Phenylpyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-amine
FR 180204
CAS: 865362-74-9
Molecular Formula: C18H13N7
5-(2-Phenylpyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-amine - Names and Identifiers
5-(2-Phenylpyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-amine - Physico-chemical Properties
| Molecular Formula | C18H13N7 |
| Molar Mass | 327.34 |
| Density | 1.55±0.1 g/cm3(Predicted) |
| Melting Point | 267 °C |
| Solubility | DMSO: ≥10mg/mL |
| Appearance | Yellow solid |
| Color | faint yellow to dark yellow |
| pKa | 7.19±0.50(Predicted) |
| Storage Condition | 2-8°C |
| In vitro study | In AP-1 transfected cells, FR 180204 dose-dependently inhibited AP-1 transactivation with an IC50 of 3.1 μm. FR 180204 inhibits spontaneous mesothelioma cell growth. |
| In vivo study | In mice with collagen-induced arthritis, FR180204 (100 mg/kg, I. P., B. I. d.) significantly reduced symptom progression and weight loss. In a mouse model injected with dengue Virus (DENV), FR180204 limits hepatocyte apoptosis, reduces DENV-induced liver injury, and improves clinical indicators. |
5-(2-Phenylpyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-amine - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R20 - Harmful by inhalation |
| WGK Germany | 3 |
| HS Code | 29339900 |
5-(2-Phenylpyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-amine - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.055 ml | 15.275 ml | 30.549 ml |
| 5 mM | 0.611 ml | 3.055 ml | 6.11 ml |
| 10 mM | 0.305 ml | 1.527 ml | 3.055 ml |
| 5 mM | 0.061 ml | 0.305 ml | 0.611 ml |
Last Update：2024-01-02 23:10:35
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Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
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Product Name: FR 180204 Visit Supplier Webpage Request for quotationCAS: 865362-74-9
Tel: +86-400-900-4166
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Mobile: +86-18621343501
QQ: 2881950922
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View History
5-(2-Phenylpyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-amine
3(2H)-Thiophenone, 4-(butylthio)-, 1,1-dioxide
ethyl cyano[(2-methyl-1H-benzimidazol-6-yl)hydrazono]acetate
Benzamide, N-(5-ethyl-4-phenyl-2-thiazolyl)-4-methoxy-3-nitro-
AKOS PAO-1544
(Oxolan-3-ylmethyl)hydrazine hydrochloride
3-Benzofurancarboxylic acid, 6-aMino-5-cyclopropyl-2-(4-fluorophenyl)-, ethyl ester
Hafnium, trichloro(2,4-pentanedionato)(tetrahydrofuran)- (8CI)
2-Chloro-1-(3,5-dihydroxyphenyl)ethanone
N-[1-(4-chlorophenyl)butyl]-3,4-dimethylaniline
3(2H)-Thiophenone, 4-(butylthio)-, 1,1-dioxide
ethyl cyano[(2-methyl-1H-benzimidazol-6-yl)hydrazono]acetate
Benzamide, N-(5-ethyl-4-phenyl-2-thiazolyl)-4-methoxy-3-nitro-
AKOS PAO-1544
(Oxolan-3-ylmethyl)hydrazine hydrochloride
3-Benzofurancarboxylic acid, 6-aMino-5-cyclopropyl-2-(4-fluorophenyl)-, ethyl ester
Hafnium, trichloro(2,4-pentanedionato)(tetrahydrofuran)- (8CI)
2-Chloro-1-(3,5-dihydroxyphenyl)ethanone
N-[1-(4-chlorophenyl)butyl]-3,4-dimethylaniline